Phys 8107
衍射光學與全像影像術:
本課程將介紹衍射光學與全像影像術的設計與理論，包含厚薄光柵、光學干涉、傅立葉光學、全像紀錄材料，並且導入生醫影像、資料儲存、光纖光柵、偏光元件的應用，此課程會將光學導論延伸至高等生物光學顯微術的實際應用。
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1 |
Basic concepts and introduction of terminology(1) Overview of applications of holography(2) Differences between holographic and lens imaging(3) Absorption and phase modulation(4) Thin and thick gratings(5) Transmission and reflection gratings |
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2 |
(1) Principles of holographic recording and reconstruction (2) Phase conjugation and time-reversed wave. |
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3 |
(1) Introduction of zone plate, (2) Review of holographic recording process, and (3) Principles of dispersion for thin gratings |
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4 |
Fourier analysis of gratings, including (1) review of Fresnel diffraction and Fraunhofer formulas, (2) diffraction patterns from apertures, and (3) Fourier analysis of absorption and phase gratings. |
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5 |
Lab #1: digital holographic imaging: recording process and computational reconstruction procedure. |
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6 |
(1) Fourier analysis of off-axis gratings, (2) difference between on-axis, and off-axis gratings, and (3) off-axis hologram reconstruction. |
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7 |
Continue on off-axis holographic topics, and review home assignment |
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8 |
Image analysis of holograms includes: (1) exact ray tracing, (2) paraxial ray tracing, and (3) aberration of holographic lenses. |
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9 |
(1) Summary of Phys' 2nd lab, and (2) introduction of coherence: temporal/spatial coherence |
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10 |
Hologram recording requirements: Coherence, visibility, polarization, and beam ratio. |
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11 |
(1) Demo: holographic microscopic setup through VH filter made in our previous lab. (2) Introduction of VH. |
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12 |
Coupled wave theory for (1) transmission and reflection gratings, (2) lossless, lossy, and absorption gratings. |
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13 |
2nd lab |
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14 |
Final project review |
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15 |
Final Exam |
Med 5036
光學造影原理及應用:
光學為基礎的影像系統，可以彌補超音波(ultrasound)、微波造影與X-ray技術的不足，提供三維成像、高解析度(high resolution)之影像。因此本課程目標為增進醫學院與醫學系學生大二(含)以上光學影像系統之原理與醫學上之應用。本課程採取循序漸進，並介紹於實際醫學之應用。
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1 |
Basic concepts and introduction of terminology: (1) Overview of applications of optical microscopy, and (2) Differences among optical microscopic imaging and other clinical imaging techniques. |
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2 |
(1) Basic applications of confocal microscopy, (2) introduction of confocal imaging, (3) difference between confocal and conventional microscopy in tissue imaging (* reference paper: attached Nature review paper) |
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3 |
Optical Microscopy Lab (I): Home-made (lab-made) basic setup of a conventional microscopic system |
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4 |
(1) Overview of phase contrast microscopy, (2) comparison between phase contrast techniques and conventional microscopy of living cells, and (3) basic concept of related phase enhanced imaging |
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5 |
Optical Microscopy Lab (II): confocal microscopic system |
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6 |
Optical Microscopy Lab (III): lab-made basic setup of digital holographic microscopic (DHM) system |
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7 |
Midterm |
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8 |
Optical Microscopy Lab (IV): fluorescence staining process |
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9 |
Optical Microscopy Lab (V): structured illumination microscopy (SIM) |
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10 |
Optical Microscopy Lab (VI): structured illumination microscopy (SIM) |
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11 |
Final project presentation group (I) |
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12 |
Guest lecture: MIT Prof. George Barbastathis; Final project presentation group (II) |