國立臺灣大學醫學院光學實驗室

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http://optics.mc.ntu.edu.tw/en/jobs

PRINCIPAL INVESTIGATOR

Yuan Luo, Associate Professor

Institute of Medical Device and Imaging; Molecular Imaging Center

National Taiwan University

E-mail: This email address is being protected from spambots. You need JavaScript enabled to view it.

Phone: 886-2-2312-3456 ext:88736;88613

Honors & Awards Received:

Young Principle Investigator Awards in Medicine (青杏醫學獎), Medical Science of Culture and Education Foundation(青杏文教基金會), Taiwan, 2018.
Ta-You Wu Memorial Award(吳大猷先生紀念獎) for Young Principle Investigators, Ministry of Science and Technology, Taiwan, 2016.
C.Y. Lee Memorial Foundation Award(李鎮源院長紀念醫學獎), National Taiwan University College of Medicine, Taiwan, 2016.
Young Principle Investigators’ Award(年輕學者獎助計畫), Ministry of Science and Technology, Taiwan, 2016-2018.
Career Development Awarded CDG Research Grant, National Health Research Institute, Taiwan, 2013-2016.
Paper Award, Laser Medical Foundation, Taiwan, 2013.
Graduate Valedictorian, College of Optical Sciences, University of Arizona, USA, 2008.
Achievement Award for Outstanding Research Assistant, Graduate and Professional Student Council (GPSC), University of Arizona, USA, 2008.
Outstanding Graduate Student Award, College of Optical Sciences, University of Arizona, USA, 2008.
Christopher Karl Schultz Memorial Scholarship, College of Optical Sciences, University of Arizona, USA, 2006.
Scholarship for Outstanding Students Studying Abroad, Ministry of Education, Taiwan, 2005-2007.

Academic Position & Education

Associate Professor, Institute of Medical Device and Imaging, National Taiwan University,
Aug. 2015 - current.
Assistant Professor, Center for Optoelectronic Biomedicine, National Taiwan University,
Aug. 2011 - Jul. 2015.
Postdoctoral Associate, Mechanical Engineering, MIT, USA,
2009-2011.
Visiting Scholar, Biosym Laboratory, Singapore-MIT Alliance for Research and Technology (SMART) Centre, Singapore,Jan. 2011-Jul.2011
Ph.D., College of Optical Sciences, University of Arizona, USA,
2004-2008 (GPA:4.0/4.0; Graduate Valedictorian of the College of Optical Sciences 2008)

Scientific Interests

Our research primary interests are in development of high-dimensional optical imaging systems, diffractive optics for high-speed sensing, as well as spatial-spectral holographic components and miniatured medical devices. Advances in those fields will lead to innovations of new optical systems that can better manipulate light for real-time and 3D imaging applications. For example, cancer is one of the leading causes of death in the world. Real-time three-dimensional (3D) imaging systems are necessary and will open the way for better understanding of the onset of cancer and biological tissue morphology as well as other clinical uses.

Education of Yuan Luo Ph.d

Education

Ph.D., College of Optical Sciences, 2004-2008
University of Arizona, USA
Dissertation: Novel Biomedical Imaging Systems
Advisor: Prof. Raymond K. Kostuk
Graduate Valedictorian of the College of Optical Sciences 2008.
GPA: 4.0

M. S., College of Optical Sciences, 2004-2007
University of Arizona, USA
GPA: 4.0

M. S., Electrical Engineering, 1995-1997
National Chung Cheng University, Taiwan
Thesis: Fractional Fourier Transform and Its Applications
Advisor: Dr. Chung J. Kuo
GPA: 4.0

B. S., Electrical Engineering, 1992-1995
National Chung Cheng University, Taiwan
Graduated with honors, and graduated early within 3 years
(ranked 1st in the graduation class)

COURSES

Phys 8107

Holographic Imaging and Diffractive Optics:

This course describes the nature of holographic and lithographically formed diffraction volume/thin gratings and necessary tools for their design and analysis. Course topics include a description of the interference and Fourier relations that determine the amplitude of diffracted fields, analysis of volume gratings, and properties of holographic recording materials, binary gratings, and analysis of applications of holography including bio-imaging and data storage, fiber Bragg gratings, and polarization control elements. This class can complement the courses of Optics and Advanced Bio-Optical Microscopy.

1	Basic concepts and introduction of terminology(1) Overview of applications of holography(2) Differences between holographic and lens imaging(3) Absorption and phase modulation(4) Thin and thick gratings(5) Transmission and reflection gratings
2	(1) Principles of holographic recording and reconstruction (2) Phase conjugation and time-reversed wave.
3	(1) Introduction of zone plate, (2) Review of holographic recording process, and (3) Principles of dispersion for thin gratings
4	Fourier analysis of gratings, including (1) review of Fresnel diffraction and Fraunhofer formulas, (2) diffraction patterns from apertures, and (3) Fourier analysis of absorption and phase gratings.
5	Lab #1: digital holographic imaging: recording process and computational reconstruction procedure.
6	(1) Fourier analysis of off-axis gratings, (2) difference between on-axis, and off-axis gratings, and (3) off-axis hologram reconstruction.
7	Continue on off-axis holographic topics, and review home assignment
8	Image analysis of holograms includes: (1) exact ray tracing, (2) paraxial ray tracing, and (3) aberration of holographic lenses.
9	(1) Summary of Phys' 2nd lab, and (2) introduction of coherence: temporal/spatial coherence
10	Hologram recording requirements: Coherence, visibility, polarization, and beam ratio.
11	(1) Demo: holographic microscopic setup through VH filter made in our previous lab. (2) Introduction of VH.
12	Coupled wave theory for (1) transmission and reflection gratings, (2) lossless, lossy, and absorption gratings.
13	2nd lab
14	Final project review
15	Final Exam

Med 5036

Optical Microscopy and Its Applications:

Introduce the basic optical image system, including 3D image and high resolution. The purpose is to promote the concept of optical image systems and applications for medical students.

1	Basic concepts and introduction of terminology: (1) Overview of applications of optical microscopy, and (2) Differences among optical microscopic imaging and other clinical imaging techniques.
2	(1) Basic applications of confocal microscopy, (2) introduction of confocal imaging, (3) difference between confocal and conventional microscopy in tissue imaging (* reference paper: attached Nature review paper)
3	Optical Microscopy Lab (I): Home-made (lab-made) basic setup of a conventional microscopic system
4	(1) Overview of phase contrast microscopy, (2) comparison between phase contrast techniques and conventional microscopy of living cells, and (3) basic concept of related phase enhanced imaging
5	Optical Microscopy Lab (II): confocal microscopic system
6	Optical Microscopy Lab (III): lab-made basic setup of digital holographic microscopic (DHM) system
7	Midterm
8	Optical Microscopy Lab (IV): fluorescence staining process
9	Optical Microscopy Lab (V): structured illumination microscopy (SIM)
10	Optical Microscopy Lab (VI): structured illumination microscopy (SIM)
11	Final project presentation group (I)
12	Guest lecture: MIT Prof. George Barbastathis; Final project presentation group (II)

研發成果

International Journal Publications:

2018
W. T. Lin, C. Y. Lin, V. R. Singh & Y. Luo “Speckle illumination non-scanning holographic (SINH) fluorescence endoscopy,” submitted, 2018.
H. H. Chen, Y. Z. Lin & Y. Luo “Isotropic differential phase contrast microscopy for quantitative phase imaging,” submitted, 2018.
2017
C. Y. Lin & Y. Luo “Simultaneous multiplane imaging with programmable multiplexed gratings,” submitted, 2017.
S. Vyas & Y. Luo “Spatial mode multiplexing using volume holographic gratings,” Optics Express, vol. 25, pp. 23726-23737, Sept. 2017.
Po-Hao Wang, Vijay Raj Singh, Jau-Min Wong, K. B. Sung & Y. Luo “Non-axial-scanning multi-focal confocal microscopy with multiplexed volume holographic gratings,” Optics Letters, vol. 42, pp. 346-9, Jan. 2017.
C. Y. Lin & Y. Luo “Simultaneous multiplane imaging with programmable multiplexed gratings,” submitted, 2017.
S. Vyas & Y. Luo “Spatial mode multiplexing using volume holographic gratings,” Optics Express, vol. 25, pp. 23726-23737, Sept. 2017.
P. H. Wang, V. R. Singh, J. M. Wong, K. B. Sung & Y. Luo “Non-axial-scanning multi-focal confocal microscopy with multiplexed volume holographic gratings,” Optics Letters, vol. 42, pp. 346-9, Jan. 2017.
2016
Y. Lv, X.Zhang, D. Zhang, L. Zhang, Yuan Luo & J. Luo “Reduction of blurring in broadband volume holographic imaging using a deconvolution method,” Biomedical Optics Expresss, vol. 7, pp. 3124-3138, Aug. 2016 (IF=3.334; ranking in Optics:9/87)
C. Y. Lin, W. T. Lin, J. H. Chien,J. C. Tsai & Yuan Luo* “In Vivo volumetric fluorescence sectioning microscopy with mechanical-scan-free hybrid illumination imaging,” Biomedical Optics Expresss, vol. 7, pp. 3968-3978, Sept. 2016.
Chen Yen Lin, Wei-Tang Lin, Hsi-Hsun Chen, Jau-Min Wong, Vijay Raj Singh and Yuan Luo "Talbot multi-focal holographic fluorescence endoscopy for optically sectioned imaging" Opt. Lett. 41, 344-347 (2016)
2015
Zhai X, Lin WT, Chen HH, Wang PH, Yeh LH, Tsai JC, Singh VR, Luo Y* "In-line digital holographic imaging in volume holographic microscopy"Opt Lett. 2015 Dec 1;40(23):5542-5.
Chia-Wei Chu, Xiaomin Zhai, Chih Jie Lee, Po-Hao Wang, Yubo Duan, Din Ping Tsai,, Baile Zhang, and Yuan Luo* “Phase-preserved macroscopic visible-light carpet cloaking beyond two dimensions,” Laser & Photonics Reviews, Volume 9, Issue 4, pages 399–404, July 2015. (SCI Optics, 3/82, IF:9.313)
Hsi-Hsun Chen, V. R. Singh, and Yuan Luo*, “Speckle-based volume holographic microscopy for optically sectioned multi-plane fluorescence imaging,” Optics Express, Vol. 23, Issue 6, pp. 7075-7084, Mar. 2015.
Hsi-Hsun Chen, Se Baek Oh, Xiaomin Zhai, Jui-Chang Tsai, Liang-Cai Cao, George Barbastathis and Yuan Luo* ,”Wigner analysis of three dimensional pupil with finite lateral aperture,” Optics Express, Vol. 23, Issue 4, pp. 4046-4054, Feb. 2015.
2014
Yuan Luo, Vijay Raj Singh, Dipanjan Bhattacharya, Elijah Y. S. Yew, Jui-Chang Tsai, Sung-Liang Yu, Hsi-Hsun Chen, Jau-Min Wong8, Paul Matsudaira, Peter T. C. So and George Barbastathis, "Talbot Holographic Illumination Non-scanning (THIN) Fluorescence Microscopy," Laser & Photonics Reviews ,Volume 8, Issue 5, pages L71–L75, September 2014. (SCI Optics, 3/82, IF:9.313)
Z. Chen, W. Chen, H.Y. Lu, Y. Chevallier, N. Chen, G. Barbastathis & Yuan Luo, "Real-time 3D particle manipulation visualized using volume holographic gratings," Optics Letters, Vol. 39 Issue 10, pp.3078-3081 ,May. 2014. (SCI Optics, 10/82, IF:3.179)(http://www.opticsinfobase.org/spotlight/summary.cfm?uri=ol-39-10-3078)
2013
Yuan Luo, B. Zhang, T. Han, Z. Chen, Y. Duan, C. W. Chu, G. Barbastathis & C. W. Qiu, “Phase-preserved optical elevator,” Optics Express, vol. 21, pp.6650-6657, Mar. 2013. (SCI Optics,3/71, IF:3.477)
S. B. Oh, Z. J. Lu, J. C. Tsai, H. H. Chen, G. Barbastathis & Yuan Luo*, “Phase-coded volume holographic gratings for spatial-spectral imaging filters,” Optics Letters, vol. 38, pp.477-479, Feb. 2013. (SCI Optics,4/71, IF:3.299)
2012
V. Singh, H. Choi, E. Yew, D. Bhattacharya, Yuan Luo, C. Sheppard, J. Rajapakse, G. Barbastathis, & P. So, “Improving signal-to-noise ratio of structured light microscopy based on photon reassignment,” Biomedical Optics Express, Jan. vol. 1, pp.206-214, Jan. 2012. ( IF: 3.176)
2011
Yuan Luo, I. K. Zervantonakis, S. Oh, R. D. Kamm, & G. Barbastathis, “Spectrally resolved multidepth fluorescence imaging,” Journal of Biomedical Optics, vol. 16, pp.096015, Sept. 2011. (SCI Optics,5/71, IF: 3.109)
Yuan Luo, E. de Leon, J. Lee, J. M. Castro, J. K. Barton, R. K. Kostuk, & G. Barbastathis, “Phase contrast volume holographic microscopy for real-time and multi-plane imaging,” Optics Letters, vol. 36, pp.1290-1292, Apr. 2011. (SCI Optics,4/71, IF:3.299)
J. M. Castro, J. Brownlee, Yuan Luo, E. de Leon, J. K. Barton, R. K. Kostuk, & G. Barbastathis, “Spatial-spectral volume holographic systems: resolution dependence on effective thickness,” under revision in Applied Optics, Jan. 2011. ( IF:1.709)
2010
B. Zhang, Yuan Luo, X. Liu, & G. Barbastathis, “Macroscopic invisible cloak for visible light,” Physical Review Letters, vol. 106, pp.033901.1-033901.4, Jan. 2011. (highlighted in Nature News, Dec. 2010, and also selected as the 4th out of the top 10 breakthrough inventions of 2010 in Physics World (http://physicsworld.com/cws/article/news/44618) in Dec. 2010) (SCI Physics,7/71, IF:7.328)
Yuan Luo, J. M. Castro, J. K. Barton, R. K. Kostuk, & G. Barbastathis, “Simulations and experiment of aperiodic and multiplexed gratings in volume holographic imaging systems,” Optics Express, vol. 19, pp.19273-19285, Aug. 2010. (SCI Optics,3/71, IF:3.477)
L. A. Waller, Yuan Luo, & G. Barbastathis, “Transport of intensity phase imaging in a volume holographic microscope,” Optics Letters, Vol. 35, pp. 2961-2963, 2010. Aug. 2010. (SCI Optics,4/71, IF:3.299)
Yuan Luo, J. M. Russo, R. K. Kostuk, & G. Barbastathis, “Silicon oxide nano-partilces doped PQ-PMMA for volume holographic filters,” Optics Letters, vol. 35, pp. 1269-1271, Apr. 2010. (SCI Optics,4/71, IF:3.299)
P. J. Gelsinger-Austin, Yuan Luo, J. M. Watson, R. K. Kostuk, G. Barbastathis, J. K. Barton, & J. M. Castro, "Optical design for a spatial-spectral volume holographic imaging system," Optical Engineering, vol. 49, pp.043001-043001-5, Apr. 2010. ( IF:0.815)
Yuan Luo, S. Oh, & G. Barbastathis, "Wavelength-coded multi-focal microscopy," Optics Letters, vol. 35, pp. 781-783, Mar. 2010. (also selected for publication in Virtual J. of Biomedical Optics, vol. 5, Iss. 6, Apr. 2010.) (SCI Optics,4/71, IF:3.299)
2008
Yuan Luo, P. J. Gelsinger-Austin, J. M. Watson, G. Barbastathis, J. K. Barton, & R. K. Kostuk, "Laser induced fluorescence imaging of sub-surface tissue structures with a volume holographic spatial-spectral imaging system," Optics Letters, vol. 33, pp. 2098-2100, Sept. 2008. (also selected for publication in Virtual J. of Biomedical Optics, vol. 3, Iss. 11, Oct. 2008.) (SCI Optics,4/71, IF:3.299)
L. J. Arauz, Yuan Luo*, J. E. Castillo, J. K. Barton, & R. K. Kostuk, "Fiber array fabrication technique for 15μm diameter single mode fibers," Optical Engineering, vol. 47, pp. 074002, Jul. 2008. ( IF:0.722)
Yuan Luo, P. J. Gelsinger, G. Barbastathis, J. K. Barton, & R. K. Kostuk, "Optimization of multiplexed holographic gratings in PQ-PMMA for spectral-spatial imaging filters," Optics Letters, vol. 33, pp. 566-568, Mar. 2008. (also selected for publication in Virtual J. of Biomedical Optics, vol. 3, Iss. 4, Apr. 2008.) (SCI Optics,4/71, IF:3.299)
Yuan Luo , L. J. Arauz, J. E. Castillo, J. K. Barton, & R. K. Kostuk, "Parallel optical coherence tomography system," Applied Optics, vol. 46, pp. 8291-8297, Dec. 2007. (also selected for publication in Virtual J. of Biomedical Optics, vol. 3, Iss. 1, Jan. 2008.) ( IF:1.763)
2007
Yuan Luo , J. E. Castillo, L. J. Arauz, J. K. Barton, & R. K. Kostuk, "Coupling and cross-talk effects in 12-15 μm diameter single-mode fiber arrays for simultaneous transmission and photon collection from scattering media," Applied Optics, vol. 46, pp. 253-261, Jan. 2007. ( IF:1.701)
2002
C.J. Kuo, N.Y. Chang & Yuan Luo, “Free-space Fresnel diffraction for the approximation of fractional Fourier transform,” Optical & Quantum Electronics, vol. 34, pp. 369~376, Apr. 2002.
1998
C.J. Kuo & Yuan Luo, "Generalized joint fractional Fourier transform correlators: a compact approach," Applied Optics, vol. 37, no. 35, pp. 8270~8276, December 1998.

Selected Invited Talks & News Articles:

"Volume Holographic Microscopy with Selective Illumination," Asian Society for Molecular Imaging (FASMIC), Taipei, Taiwan, Oct. 2013.
"Volume Holographic Pupils for Imaging," International Workshop on Holography and Related Technologies, Hokkaido, Japan, Oct. 2013.
"Spatial-Spectral Sensing and Imaging," NSCF-NSC Bioimaging Meeting, Shenzhen, China, Sep. 2013.
"Spatial-Spectral Volume Holographic Imaging," Asian Biophysics Association Symposium, Jeju, Korea, May 2013.
"Spatial-Spectral Holographic System for Tissue Imaging," International Workshop on Holography and Related Technologies, Taoyuan, Taiwan, Oct. 2012.
"Spatial-Spectral Volume Holographic Systems for Tissue Imaging," Japan Associate of Medical Spectroscopy, Tokyo, Japan, Oct., 2012.
"Volume Holographic Gratings for Spatial-Spectral Optical Imaging Systems," PIERS, KL, Malaysia, Apr., 2012.
"Unconventional Optics: Spatial-Spectral Imaging," National Central University, Taoyuan, Oct., 2011.
"Spectrum-Resolved Fluorescence Imaging in Multifocal Volume Holographic Microscopy," SPIE Photonics West, San Francisco, Jan., 2011.
"4D Volume Holographic Microscopy and Cloak for Visible Light," Delta Electronics Inc., Taiwan, Jan., 2011.
B. Zhang, Yuan Luo, X. Liu, & G. Barbastathis" Macroscopic invisible cloak for visible light," highlighted in Nature News, Dec. 2010. (also selected as the 4th out of the top 10 breakthrough inventions of 2010 in Physics World, Dec. 2010 (http://physicsworld.com/cws/article/news/44618))
Yuan Luo, I. Zervantonakis, S, Oh, R. Kamm & G. Barbastathis" Volume holographic microscopy shows cell depths in real-time," SPIE Newsroom, Nov. 2010.
"Spatial-Spectral Volume Holographic Imaging System," OSA/CIPS Brown Bag Seminar at MIT, USA, November, 2009.
"Spatial-Spectral Volume Holographic Imaging System," National Institute of Standards and Technology (NIST)/Industry Polymer Surface/Interface Consortium Meeting, June, 2009.
"Hyper-spectral Imaging System and 4D Holographic Microscope," National Institute of Health (NIH), May, 2009.
"Spatial Spectral Volume Holographic Imaging System," National Institute of Standards and Technology (NIST), March, 2009.

Patents:

"System, method and apparatus for contrast enhanced multiplexing of images", US No. 13/500467.
"Phase-Encoded Multiplane Microscope", M.I.T. Case No. 14668.
"Wavelength-Coded Multi-Focal Microscope", M.I.T. Case No. 13942.
"Contrast-Enhanced Multiplexing Imaging", M.I.T. Case No. 13982.

Recent 5-Year Conference Publications:

Yuan Luo "Spatial-Spectral Volume Holographic Imaging," SPIE DSS Conference, Baltimore, USA, Apr. 2015.
Po-Hao Wang, and Yuan Luo "Self-interference low-coherent digital holography by engineered volume holographic pupils," OSA Optical Meeting: Digital Holography & 3D Imaging, Shanghai, China, Apr. 2015.
H. H. Chen, V. R. Singh, and Yuan Luo "Speckle-based Volume Holographic Microscopy for Optically Sectioned Multi-depth Fluorescent Imaging," OSA Optical Meeting: Digital Holography & 3D Imaging, Shanghai, China, Apr. 2015.
Yuan Luo "Non-scanning 3D Holographic Fluorescence Microscopy for Tissue Imaging," Biophotonics and Optical Biomedicine Symposium at ICMAT 2015, Singapore, Jun. 2015. (Invited)
Xiaomin Zhai, Yuan Luo, “Non-scanning holographic light-sheet fluorescence microscopy for multi-plane imaging”, The 5^th NTU Biomedical Molecular Imaging, SiTou, Nov. 2015.
Yuan Luo "Spatial-Spectral Holographic Fluorescence Microscopy for Tissue Imaging," The 5^th NTU Biomedical Molecular Imaging, SiTou, Nov. 2015. (Invited)
X. Zhai, P. H. Wang, H. H. Chen, W. T. Lin, and Yuan Luo "3D Pupil Engineered Holographic Imaging," Internal Workshop of Holography (IWH), Japan, Dec. 2015. (Invited)
Xiaomin Zhai; Chen Yen Lin; His-Hsun Chen; Jui-Chang Tsai; Sung-Liang Yu; Yuan Luo, “Holographic light-sheet fluorescence microscopy for one-shot multi-plane imaging” Optics & Photonics Taiwan, the International Conference (OPTIC), Hsinchu, Taiwan, Dec. 2015.
"Volume Holographic Microscopy with Selective Illumination," Asian Society for Molecular Imaging (FASMIC), Taipei, Taiwan, Oct. 2013. (invited)
"Volume Holographic Pupils for Imaging," International Workshop on Holography and Related Technologies, Hokkaido, Japan, Oct. 2013. (invited)
"Transformation Optics Based Lift for Large View-Angle, Phase-Undisturbed Optical Imaging" JASP-OSA Joint Symposium, Japan, Sept. 2013
"Spatial-Spectral Sensing and Imaging," NSCF-NSC Bioimaging Meeting, Shenzhen, China, Sept. 2013. (invited)
“Phase filter embedded volume holographic imaging,” International Symposium on Photo-electronic Detection and Imaging, Bejing, China, June, 2013.
"Spatial-Spectral Volume Holographic Imaging," Asian Biophysics Association Symposium, Jeju, South Korea, May. 2013. (invited)
"Spatial Filter Encoded Volume Holographic Gratings in PQ-PMMA for Spatial-Spectral Imaging," SPIE photonics West, San Francisco, USA, Jan. 2013 .
"Spatial-Spectral Volume Holographic Systems for Tissue Imaging," Japan Associate of Medical Spectroscopy, Tokyo, Japan, Oct., 2012.
Yuan Luo, & G. Barbastathis" Volume Holographic Gratings for Spatial-Spectral Optical Imaging Systems," PIERS, Kuala Lumpur, Malaysia, Mar. 2012.
Yuan Luo, & G. Barbastathis" Unconventional Spatial-Spectral Sensing and Imaging," IEEE the 8th international networked sensor, Taiwan, Jun. 2011.
Yuan Luo, & G. Barbastathis" Phase-Coded Volume Holographic Microscopy," SPIE Biomedical Optics, Munich, Germany, May. 2011.
Yuan Luo, I. Zervantonakis, S, Oh, R. Kamm & G. Barbastathis" Spectrum-resolved fluorescence imaging in multifocal volume holographic microscopy," SPIE photonics West, San Francisco, USA, Jan. 2011.
L. Waller, Yuan Luo, and G. Barbastathis, “Quantitative phase imaging in a volume holographic microscope,” Advanced Phase Measurement Methods in Optics and Imaging, Switzerland, May, 2010.
Yuan Luo, S. Oh, S. Kou, C. J. R. Sheppard, & G. Barbastathis" Image Formation of Volume Holographic Microscopy Using Intensity Point Spread Functions," SPIE Symposium on Medical Imaging 2010, San Diego, USA, Feb. 2010.
Yuan Luo, P. J. Gelsinger, E. D. Leon, J. Harwell, J. K. Barton, R. K. Kostuk, & G. Barbastathis" Phase Contrast Volume Holographic Microscope," Frontiers in Optics 2009, San Jose, USA, Oct. 2009.
Yuan Luo, P. J. Gelsinger, J. K. Barton, R. K. Kostuk, & G. Barbastathis" Spectral-Spatial Depth Sectioning of Biological Samples Using Silicon Oxide Nano-Particles Doped PQ-PMMA," OSA topics meeting, Vancouver, Canada, Apr. 2009.

RESEARCH

Beam shaping using Multiplexed Volume Holographic Gratings

We experimentally demonstrate spatial mode multiplexing of optical beams using multiplexed volume holographic gratings (MVGHs) formed in phenanthrenquinone-poly(methyl methacrylate) (PQ-PMMA) photopolymer. Multiple spatial modes of Laguerre-Gaussian (LG) beams are recorded at the same pupil area of a volume hologram resulting in MVHGs, for simultaneous reconstruction of spatial modes. In addition, a helical phase beam, a non-diffracting beam with conical phase profile, and a parabolic non-diffracting beam with cubic phase profile have also been simultaneously recorded and reconstructed from MVHGs. Utilizing Bragg wavelength degeneracy property of volume hologram these multiplexed modes are reconstructed at multiple wavelengths ranging from blue (450nm) to red (635). Due to combined effect of three-dimensional pupil, Bragg wavelength degeneracy, angular selectivity, together with spatial mode properties these, MVHGs can act as spatial mode filter with spectral filtering property. Advantages of volume holography in beam shaping are discussed. Multiple first diffraction orders with desired beam shapes obtained from the single optical element (i.e. a volume hologram with MVHGs) may find important applications in optical communication experiments, and in volume holographic imaging and microscopy. Experimental results show solid evidence that MVGHs in beam shaping provide a simple, compact, single element, and direct way to multiplex spatial modes.

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Multiplane Holographic Non-scanning Endoscopy:

( Recent publication Chen Yen Lin, Wei-Tang Lin, Hsi-Hsun Chen, Jau-Min Wong, Vijay Raj Singh, and Yuan Luo, "Talbot multi-focal holographic fluorescence endoscopy for optically sectioned imaging," Opt. Lett. 41, 344-347 (2016))

A wide-field multi-plane endoscopic system incorporating multiplexed volume holographic gratings and Talbot illumination to simultaneously acquire optically sectioned fluorescence images of tissue structures from different depths is presented. The proposed endoscopic system is configured such that multiple Talbot-illumination planes occur inside a volumetric sample and serve as the input focal planes for the subsequent multiplexed volume holographic imaging gratings. We describe the design, implementation, and experimental data demonstrating this endoscopic system’s ability to obtain optically sectioned multi-plane fluorescent images of tissue samples in wide-field fashion without scanning in lateral and axial directions.

Multiplane Holographic Non-scanning microscopy:

( Recent publication LPR: pp. L71–L75, 2014; OE: pp. 7075-7084, 2015; OE: pp. 4046-4054, 2015 )

Optical sectioning techniques offer the ability to acquire three-dimensional information from various organ tissues by discriminating between the desired in-focus and out-of-focus (background) signals. Alternative techniques to confocal, such as active structured illumination, exist for fast optically sectioned images, but they require individual axial planes to be imaged consecutively. In this article, an imaging technique (THIN), by utilizing active Talbot illumination in 3D and multiplexed holographic Bragg filters for depth discrimination, is demonstrated for imaging in vivo 3D biopsy without mechanical or optical axial scanning.

Phase-preserved macroscopic visible-light carpet cloaking beyond two dimensions:
( Recent publication LPR: pp. 399–404, 2015; OE: pp.6650-6657, 2013 )

Transformation optics, a recent geometrical design strategy of light manipulation with both ray trajectories and optical phase controlled simultaneously, promises without precedent an invisibility cloaking device that can render a macroscopic object invisible even to a scientific instrument measuring optical phase. However, previous macroscopic cloaks only demonstrated the recovery of ray trajectories after passing through the cloaks, while whether the optical phase would reveal their existence still remains unverified. In this paper, a phase- preserved macroscopic visible-light cloak is demonstrated in a geometrical construction beyond two dimensions. As an extension of previous two-dimensional (2D) macroscopic cloaks, this almost-three-dimensional cloak exhibits three-dimensional (3D) invisibility for illumination near its center (i.e. with a limited field of view), and its ideal wide-angle invisibility performance is preserved in multiple 2D planes intersecting in the 3D space. Optical path length is measured with a broadband pulsed-laser interferometer, which provides unique experimental evidence on the geometrical nature of transformation optics.

Nano-SiO2 in PQ-PMMA for Holographic Filters in Imaging:

Holographic filters in imaging/data storage/communications are required to have high Bragg selectivity, namely narrow angular and spectral bandwidth, to obtain spatial-spectral information within a three-dimensional object. The holographic filters with optimized ratio of nano-SiO2 in PQ-PMMA can significantly improve the performance of Bragg selectivity and diffraction efficiency by 53% and 16%, respectively.

Images at two depths within a grapefruit obtained using two multiplexed holographic nano-SiO2 PQ-PPMA filters.

Wavelength-Coded Holographic Microscopy:

A wavelength-coded multifocal microscope incorporates multiplexed and wavelength-coded holographic gratings to generate wavelength-selective multifocal planes. The focal planes are longitudinally spaced on the object plane, and each focal plane is probed by a designated wavelength. The recording of the multiplexed gratings takes place at a single wavelength by utilizing the Bragg degeneracy property; thus the maximum sensitive wavelength of blue 488 nm is used for recording, but the device is operated at a broad wavelength band of interest, all the way to red 633 nm.

Figure on the left shows Two depth-resolved images of an onion obtained with wavelength-coded multifocal microscopy using both blue and red LEDs for illumination. Figure in the middle shows One of the two depth-resolved images obtained with wavelength-coded multifocal microscopy when the blue LED is on and red one is off. Figure on the right shows One of the two depth-resolved images obtained with wavelength-coded multifocal microscopy when the red LED is on and blue one is off.

Spatial-Spectral Fluorescence Imaging:

A three-dimensional imaging system incorporating multiplexed holographic gratings is able to visualize fluorescence tissue structures. Holographic gratings formed in volume recording materials such as PQ-PMMA photopolymer have narrowband angular and spectral transmittance filtering properties which enable obtaining spatial-spectral information within an object. The imaging system’s ability is demonstrated to obtain multiple depth-resolved fluorescence images.

Figure on the left shows the experimental system setup, and figure on the right shows two depth-resolved images of a mouse colon.

Parallel Optical Coherence Tomography (POCT):

Optical coherence tomography (OCT) shows great promise to produce micrometer-resolution images from deep with scattering media such as biological tissues. POCT system Compared to conventional OCT systems, the POCT system is a novel technology that replaces transverse scanning in the lateral dimension with electronic scanning. This will reduce the time required to acquire image data. The POCT system consists of a single mode fiber array with multiple reduced diameter (15µm) single mode fibers in the sample arm. The POCT imaging system can therefore be adapted to an endoscopic format for detecting cancerous structures in tissues.

Figure (a) Experimental setup of the POCT system. Figure (b) POCT image of tangerine (Citrus reticulate) flesh. The tangerine’s juice vacuoles are clearly visible.

Design and Fabrication of Micro-Diameter Single-Mode-Fiber Array for Endoscopic Probe Tip:

The single mode fibers in the array can be used in coherent imaging applications such as optical coherence tomography (OCT). Fiber to substrate and fiber to fiber coupling effects were studied using beam propagation and Monte Carlo techniques to determine the different design characteristics and the maximum length of the reduced diameter fiber that can be packaged in the probe tip. Single mode fibers are etched to reduce the cladding diameter from 125 microns to 15 microns. A 2 microns thick silica layer is grown in the silicon substrate to minimize the fiber-substrate coupling. Reduced diameter fibers are placed into a 5mm by 150 microns trench etched in a silicon-silica substrate and fixed with UV curable cement. Active alignment was used to ensure the correct alignment of fibers.

Picture of the etched fiber section next to a mask with 25 micron squares

Zoomed in on the fiber array with 8 channels and silicon trench.

Schematic of linear fiber array with 15 channels and silicon trench groove.

PUBLICATIONS

International Journal Publications:

2018
W. T. Lin, C. Y. Lin, V. R. Singh & Y. Luo “Speckle illumination non-scanning holographic (SINH) fluorescence endoscopy,” submitted, 2018.
H. H. Chen, Y. Z. Lin & Y. Luo “Isotropic differential phase contrast microscopy for quantitative phase imaging,” submitted, 2018.
2017
C. Y. Lin & Y. Luo “Simultaneous multiplane imaging with programmable multiplexed gratings,” submitted, 2017.
S. Vyas & Y. Luo “Spatial mode multiplexing using volume holographic gratings,” Optics Express, vol. 25, pp. 23726-23737, Sept. 2017.
Po-Hao Wang, Vijay Raj Singh, Jau-Min Wong, K. B. Sung & Y. Luo “Non-axial-scanning multi-focal confocal microscopy with multiplexed volume holographic gratings,” Optics Letters, vol. 42, pp. 346-9, Jan. 2017.
C. Y. Lin & Y. Luo “Simultaneous multiplane imaging with programmable multiplexed gratings,” submitted, 2017.
S. Vyas & Y. Luo “Spatial mode multiplexing using volume holographic gratings,” Optics Express, vol. 25, pp. 23726-23737, Sept. 2017.
P. H. Wang, V. R. Singh, J. M. Wong, K. B. Sung & Y. Luo “Non-axial-scanning multi-focal confocal microscopy with multiplexed volume holographic gratings,” Optics Letters, vol. 42, pp. 346-9, Jan. 2017.
2016
Y. Lv, X.Zhang, D. Zhang, L. Zhang, Yuan Luo & J. Luo “Reduction of blurring in broadband volume holographic imaging using a deconvolution method,” Biomedical Optics Expresss, vol. 7, pp. 3124-3138, Aug. 2016 (IF=3.334; ranking in Optics:9/87)
C. Y. Lin, W. T. Lin, J. H. Chien,J. C. Tsai & Yuan Luo* “In Vivo volumetric fluorescence sectioning microscopy with mechanical-scan-free hybrid illumination imaging,” Biomedical Optics Expresss, vol. 7, pp. 3968-3978, Sept. 2016.
Chen Yen Lin, Wei-Tang Lin, Hsi-Hsun Chen, Jau-Min Wong, Vijay Raj Singh and Yuan Luo "Talbot multi-focal holographic fluorescence endoscopy for optically sectioned imaging" Opt. Lett. 41, 344-347 (2016)
2015
Zhai X, Lin WT, Chen HH, Wang PH, Yeh LH, Tsai JC, Singh VR, Luo Y* "In-line digital holographic imaging in volume holographic microscopy"Opt Lett. 2015 Dec 1;40(23):5542-5.
Chia-Wei Chu, Xiaomin Zhai, Chih Jie Lee, Po-Hao Wang, Yubo Duan, Din Ping Tsai,, Baile Zhang, and Yuan Luo* “Phase-preserved macroscopic visible-light carpet cloaking beyond two dimensions,” Laser & Photonics Reviews, Volume 9, Issue 4, pages 399–404, July 2015. (SCI Optics, 3/82, IF:9.313)
Hsi-Hsun Chen, V. R. Singh, and Yuan Luo*, “Speckle-based volume holographic microscopy for optically sectioned multi-plane fluorescence imaging,” Optics Express, Vol. 23, Issue 6, pp. 7075-7084, Mar. 2015.
Hsi-Hsun Chen, Se Baek Oh, Xiaomin Zhai, Jui-Chang Tsai, Liang-Cai Cao, George Barbastathis and Yuan Luo* ,”Wigner analysis of three dimensional pupil with finite lateral aperture,” Optics Express, Vol. 23, Issue 4, pp. 4046-4054, Feb. 2015.
2014
Yuan Luo, Vijay Raj Singh, Dipanjan Bhattacharya, Elijah Y. S. Yew, Jui-Chang Tsai, Sung-Liang Yu, Hsi-Hsun Chen, Jau-Min Wong8, Paul Matsudaira, Peter T. C. So and George Barbastathis, "Talbot Holographic Illumination Non-scanning (THIN) Fluorescence Microscopy," Laser & Photonics Reviews ,Volume 8, Issue 5, pages L71–L75, September 2014. (SCI Optics, 3/82, IF:9.313)
Z. Chen, W. Chen, H.Y. Lu, Y. Chevallier, N. Chen, G. Barbastathis & Yuan Luo, "Real-time 3D particle manipulation visualized using volume holographic gratings," Optics Letters, Vol. 39 Issue 10, pp.3078-3081 ,May. 2014. (SCI Optics, 10/82, IF:3.179)(http://www.opticsinfobase.org/spotlight/summary.cfm?uri=ol-39-10-3078)
2013
Yuan Luo, B. Zhang, T. Han, Z. Chen, Y. Duan, C. W. Chu, G. Barbastathis & C. W. Qiu, “Phase-preserved optical elevator,” Optics Express, vol. 21, pp.6650-6657, Mar. 2013. (SCI Optics,3/71, IF:3.477)
S. B. Oh, Z. J. Lu, J. C. Tsai, H. H. Chen, G. Barbastathis & Yuan Luo*, “Phase-coded volume holographic gratings for spatial-spectral imaging filters,” Optics Letters, vol. 38, pp.477-479, Feb. 2013. (SCI Optics,4/71, IF:3.299)
2012
V. Singh, H. Choi, E. Yew, D. Bhattacharya, Yuan Luo, C. Sheppard, J. Rajapakse, G. Barbastathis, & P. So, “Improving signal-to-noise ratio of structured light microscopy based on photon reassignment,” Biomedical Optics Express, Jan. vol. 1, pp.206-214, Jan. 2012. ( IF: 3.176)
2011
Yuan Luo, I. K. Zervantonakis, S. Oh, R. D. Kamm, & G. Barbastathis, “Spectrally resolved multidepth fluorescence imaging,” Journal of Biomedical Optics, vol. 16, pp.096015, Sept. 2011. (SCI Optics,5/71, IF: 3.109)
Yuan Luo, E. de Leon, J. Lee, J. M. Castro, J. K. Barton, R. K. Kostuk, & G. Barbastathis, “Phase contrast volume holographic microscopy for real-time and multi-plane imaging,” Optics Letters, vol. 36, pp.1290-1292, Apr. 2011. (SCI Optics,4/71, IF:3.299)
J. M. Castro, J. Brownlee, Yuan Luo, E. de Leon, J. K. Barton, R. K. Kostuk, & G. Barbastathis, “Spatial-spectral volume holographic systems: resolution dependence on effective thickness,” under revision in Applied Optics, Jan. 2011. ( IF:1.709)
2010
B. Zhang, Yuan Luo, X. Liu, & G. Barbastathis, “Macroscopic invisible cloak for visible light,” Physical Review Letters, vol. 106, pp.033901.1-033901.4, Jan. 2011. (highlighted in Nature News, Dec. 2010, and also selected as the 4th out of the top 10 breakthrough inventions of 2010 in Physics World (http://physicsworld.com/cws/article/news/44618) in Dec. 2010) (SCI Physics,7/71, IF:7.328)
Yuan Luo, J. M. Castro, J. K. Barton, R. K. Kostuk, & G. Barbastathis, “Simulations and experiment of aperiodic and multiplexed gratings in volume holographic imaging systems,” Optics Express, vol. 19, pp.19273-19285, Aug. 2010. (SCI Optics,3/71, IF:3.477)
L. A. Waller, Yuan Luo, & G. Barbastathis, “Transport of intensity phase imaging in a volume holographic microscope,” Optics Letters, Vol. 35, pp. 2961-2963, 2010. Aug. 2010. (SCI Optics,4/71, IF:3.299)
Yuan Luo, J. M. Russo, R. K. Kostuk, & G. Barbastathis, “Silicon oxide nano-partilces doped PQ-PMMA for volume holographic filters,” Optics Letters, vol. 35, pp. 1269-1271, Apr. 2010. (SCI Optics,4/71, IF:3.299)
P. J. Gelsinger-Austin, Yuan Luo, J. M. Watson, R. K. Kostuk, G. Barbastathis, J. K. Barton, & J. M. Castro, "Optical design for a spatial-spectral volume holographic imaging system," Optical Engineering, vol. 49, pp.043001-043001-5, Apr. 2010. ( IF:0.815)
Yuan Luo, S. Oh, & G. Barbastathis, "Wavelength-coded multi-focal microscopy," Optics Letters, vol. 35, pp. 781-783, Mar. 2010. (also selected for publication in Virtual J. of Biomedical Optics, vol. 5, Iss. 6, Apr. 2010.) (SCI Optics,4/71, IF:3.299)
2008
Yuan Luo, P. J. Gelsinger-Austin, J. M. Watson, G. Barbastathis, J. K. Barton, & R. K. Kostuk, "Laser induced fluorescence imaging of sub-surface tissue structures with a volume holographic spatial-spectral imaging system," Optics Letters, vol. 33, pp. 2098-2100, Sept. 2008. (also selected for publication in Virtual J. of Biomedical Optics, vol. 3, Iss. 11, Oct. 2008.) (SCI Optics,4/71, IF:3.299)
L. J. Arauz, Yuan Luo*, J. E. Castillo, J. K. Barton, & R. K. Kostuk, "Fiber array fabrication technique for 15μm diameter single mode fibers," Optical Engineering, vol. 47, pp. 074002, Jul. 2008. ( IF:0.722)
Yuan Luo, P. J. Gelsinger, G. Barbastathis, J. K. Barton, & R. K. Kostuk, "Optimization of multiplexed holographic gratings in PQ-PMMA for spectral-spatial imaging filters," Optics Letters, vol. 33, pp. 566-568, Mar. 2008. (also selected for publication in Virtual J. of Biomedical Optics, vol. 3, Iss. 4, Apr. 2008.) (SCI Optics,4/71, IF:3.299)
Yuan Luo , L. J. Arauz, J. E. Castillo, J. K. Barton, & R. K. Kostuk, "Parallel optical coherence tomography system," Applied Optics, vol. 46, pp. 8291-8297, Dec. 2007. (also selected for publication in Virtual J. of Biomedical Optics, vol. 3, Iss. 1, Jan. 2008.) ( IF:1.763)
2007
Yuan Luo , J. E. Castillo, L. J. Arauz, J. K. Barton, & R. K. Kostuk, "Coupling and cross-talk effects in 12-15 μm diameter single-mode fiber arrays for simultaneous transmission and photon collection from scattering media," Applied Optics, vol. 46, pp. 253-261, Jan. 2007. ( IF:1.701)
2002
C.J. Kuo, N.Y. Chang & Yuan Luo, “Free-space Fresnel diffraction for the approximation of fractional Fourier transform,” Optical & Quantum Electronics, vol. 34, pp. 369~376, Apr. 2002.
1998
C.J. Kuo & Yuan Luo, "Generalized joint fractional Fourier transform correlators: a compact approach," Applied Optics, vol. 37, no. 35, pp. 8270~8276, December 1998.

Selected Invited Talks & News Articles:

"Volume Holographic Microscopy with Selective Illumination," Asian Society for Molecular Imaging (FASMIC), Taipei, Taiwan, Oct. 2013.
"Volume Holographic Pupils for Imaging," International Workshop on Holography and Related Technologies, Hokkaido, Japan, Oct. 2013.
"Spatial-Spectral Sensing and Imaging," NSCF-NSC Bioimaging Meeting, Shenzhen, China, Sep. 2013.
"Spatial-Spectral Volume Holographic Imaging," Asian Biophysics Association Symposium, Jeju, Korea, May 2013.
"Spatial-Spectral Holographic System for Tissue Imaging," International Workshop on Holography and Related Technologies, Taoyuan, Taiwan, Oct. 2012.
"Spatial-Spectral Volume Holographic Systems for Tissue Imaging," Japan Associate of Medical Spectroscopy, Tokyo, Japan, Oct., 2012.
"Volume Holographic Gratings for Spatial-Spectral Optical Imaging Systems," PIERS, KL, Malaysia, Apr., 2012.
"Unconventional Optics: Spatial-Spectral Imaging," National Central University, Taoyuan, Oct., 2011.
"Spectrum-Resolved Fluorescence Imaging in Multifocal Volume Holographic Microscopy," SPIE Photonics West, San Francisco, Jan., 2011.
"4D Volume Holographic Microscopy and Cloak for Visible Light," Delta Electronics Inc., Taiwan, Jan., 2011.
B. Zhang, Yuan Luo, X. Liu, & G. Barbastathis" Macroscopic invisible cloak for visible light," highlighted in Nature News, Dec. 2010. (also selected as the 4th out of the top 10 breakthrough inventions of 2010 in Physics World, Dec. 2010 (http://physicsworld.com/cws/article/news/44618))
Yuan Luo, I. Zervantonakis, S, Oh, R. Kamm & G. Barbastathis" Volume holographic microscopy shows cell depths in real-time," SPIE Newsroom, Nov. 2010.
"Spatial-Spectral Volume Holographic Imaging System," OSA/CIPS Brown Bag Seminar at MIT, USA, November, 2009.
"Spatial-Spectral Volume Holographic Imaging System," National Institute of Standards and Technology (NIST)/Industry Polymer Surface/Interface Consortium Meeting, June, 2009.
"Hyper-spectral Imaging System and 4D Holographic Microscope," National Institute of Health (NIH), May, 2009.
"Spatial Spectral Volume Holographic Imaging System," National Institute of Standards and Technology (NIST), March, 2009.

Patents:

"System, method and apparatus for contrast enhanced multiplexing of images", US No. 13/500467.
"Phase-Encoded Multiplane Microscope", M.I.T. Case No. 14668.
"Wavelength-Coded Multi-Focal Microscope", M.I.T. Case No. 13942.
"Contrast-Enhanced Multiplexing Imaging", M.I.T. Case No. 13982.

Recent 5-Year Conference Publications:

Yuan Luo "Spatial-Spectral Volume Holographic Imaging," SPIE DSS Conference, Baltimore, USA, Apr. 2015.
Po-Hao Wang, and Yuan Luo "Self-interference low-coherent digital holography by engineered volume holographic pupils," OSA Optical Meeting: Digital Holography & 3D Imaging, Shanghai, China, Apr. 2015.
H. H. Chen, V. R. Singh, and Yuan Luo "Speckle-based Volume Holographic Microscopy for Optically Sectioned Multi-depth Fluorescent Imaging," OSA Optical Meeting: Digital Holography & 3D Imaging, Shanghai, China, Apr. 2015.
Yuan Luo "Non-scanning 3D Holographic Fluorescence Microscopy for Tissue Imaging," Biophotonics and Optical Biomedicine Symposium at ICMAT 2015, Singapore, Jun. 2015. (Invited)
Xiaomin Zhai, Yuan Luo, “Non-scanning holographic light-sheet fluorescence microscopy for multi-plane imaging”, The 5^th NTU Biomedical Molecular Imaging, SiTou, Nov. 2015.
Yuan Luo "Spatial-Spectral Holographic Fluorescence Microscopy for Tissue Imaging," The 5^th NTU Biomedical Molecular Imaging, SiTou, Nov. 2015. (Invited)
X. Zhai, P. H. Wang, H. H. Chen, W. T. Lin, and Yuan Luo "3D Pupil Engineered Holographic Imaging," Internal Workshop of Holography (IWH), Japan, Dec. 2015. (Invited)
Xiaomin Zhai; Chen Yen Lin; His-Hsun Chen; Jui-Chang Tsai; Sung-Liang Yu; Yuan Luo, “Holographic light-sheet fluorescence microscopy for one-shot multi-plane imaging” Optics & Photonics Taiwan, the International Conference (OPTIC), Hsinchu, Taiwan, Dec. 2015.
"Volume Holographic Microscopy with Selective Illumination," Asian Society for Molecular Imaging (FASMIC), Taipei, Taiwan, Oct. 2013. (invited)
"Volume Holographic Pupils for Imaging," International Workshop on Holography and Related Technologies, Hokkaido, Japan, Oct. 2013. (invited)
"Transformation Optics Based Lift for Large View-Angle, Phase-Undisturbed Optical Imaging" JASP-OSA Joint Symposium, Japan, Sept. 2013
"Spatial-Spectral Sensing and Imaging," NSCF-NSC Bioimaging Meeting, Shenzhen, China, Sept. 2013. (invited)
“Phase filter embedded volume holographic imaging,” International Symposium on Photo-electronic Detection and Imaging, Bejing, China, June, 2013.
"Spatial-Spectral Volume Holographic Imaging," Asian Biophysics Association Symposium, Jeju, South Korea, May. 2013. (invited)
"Spatial Filter Encoded Volume Holographic Gratings in PQ-PMMA for Spatial-Spectral Imaging," SPIE photonics West, San Francisco, USA, Jan. 2013 .
"Spatial-Spectral Volume Holographic Systems for Tissue Imaging," Japan Associate of Medical Spectroscopy, Tokyo, Japan, Oct., 2012.
Yuan Luo, & G. Barbastathis" Volume Holographic Gratings for Spatial-Spectral Optical Imaging Systems," PIERS, Kuala Lumpur, Malaysia, Mar. 2012.
Yuan Luo, & G. Barbastathis" Unconventional Spatial-Spectral Sensing and Imaging," IEEE the 8th international networked sensor, Taiwan, Jun. 2011.
Yuan Luo, & G. Barbastathis" Phase-Coded Volume Holographic Microscopy," SPIE Biomedical Optics, Munich, Germany, May. 2011.
Yuan Luo, I. Zervantonakis, S, Oh, R. Kamm & G. Barbastathis" Spectrum-resolved fluorescence imaging in multifocal volume holographic microscopy," SPIE photonics West, San Francisco, USA, Jan. 2011.
L. Waller, Yuan Luo, and G. Barbastathis, “Quantitative phase imaging in a volume holographic microscope,” Advanced Phase Measurement Methods in Optics and Imaging, Switzerland, May, 2010.
Yuan Luo, S. Oh, S. Kou, C. J. R. Sheppard, & G. Barbastathis" Image Formation of Volume Holographic Microscopy Using Intensity Point Spread Functions," SPIE Symposium on Medical Imaging 2010, San Diego, USA, Feb. 2010.
Yuan Luo, P. J. Gelsinger, E. D. Leon, J. Harwell, J. K. Barton, R. K. Kostuk, & G. Barbastathis" Phase Contrast Volume Holographic Microscope," Frontiers in Optics 2009, San Jose, USA, Oct. 2009.
Yuan Luo, P. J. Gelsinger, J. K. Barton, R. K. Kostuk, & G. Barbastathis" Spectral-Spatial Depth Sectioning of Biological Samples Using Silicon Oxide Nano-Particles Doped PQ-PMMA," OSA topics meeting, Vancouver, Canada, Apr. 2009.

PUBLICATIONS

广征人才

PRINCIPAL INVESTIGATOR

Education of Yuan Luo Ph.d

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研發成果

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